Figure 4

(A) Section through hepatopancreas (control) showing the normal architecture of hepatopancreatic tubule (ht), lumen (L). (B) At 10 ng/l TBT exposure, hepatopancreas showing reduction in the size of the hepatopancreatic tubule (↑ ht) and abnormal lumen (AL) (C) hepatopancreas showing reduction in the size of the hepatopancreatic tubule (↑ ht) and abnormal lumen (AL) at 100 ng/l TBT exposure, (D) At 1000 ng/l TBT exposure, hepatopancreas showing the reduction in size of the hepatopancreatic tubule (↑ ht), abnormal lumen (AL) and the disassociated epithelial cells from the hepatopancreatic tubules. Note the variation in size and arrangement of hepatopancreatic tubules in control and TBT treated groups (n = 3). Bar: 50 μm.