Protein attributes contribute to halo-stability, bioinformatics approach

Ebrahimie, Esmaeil; Ebrahimi, Mansour; Sarvestani, Narjes Rahpayma; Ebrahimi, Mahdi

doi:10.1186/1746-1448-7-1

Aquatic Biosystems

Table 2 The most important protein attributes selected by all used attribute weighting algorithms in this study.

From: Protein attributes contribute to halo-stability, bioinformatics approach

Chi Square		Deviation		Gini Index		Uncertainty		Relief		SVM		PCA
Freq of Cys	1.00	hydrogen	1.00	Count of hydrogen	1.00	Freq of Val-Gln	1.00	Hydrogen	1.00	Freq of Lys-Val	1.00	Count of Ser-Leu	1.00
Freq of Asn	1.00	Freq of Leu-Val	0.95	Freq of Val	0.85	Freq of Ala-Val	0.96	Freq of carbon	0.98	Freq of Val-Ile	0.97	Count of Ile	1.00
Freq of Val	0.99	Freq of Thr-Val	0.95	Freq of Leu-Val	0.81	Freq of Leu-Val	0.95	Freq of oxygen	0.90	Freq of Lys-Cys	0.93	Count of Met	0.93
Freq of Lys	0.95	Freq of Val	0.88	Freq of Thr-Val	0.81	Freq of Thr-Val	0.92	Freq of Hydrophobic Residues	0.89	Freq of Asn-Asn	0.93	Count of Phe	0.92
Freq of Leu-Val	0.94	Freq of Leu-Arg	0.88	Freq of Val-Val	0.79	Freq of Gly-Leu	0.91	Freq of Leu	0.85	Freq of Glu-Met	0.92	Count of Leu-Ser	0.89
Freq of Val-Gln	0.93	Freq of Leu	0.88	Freq of Ala-Tyr	0.78	hydrogen	0.90	Freq of nitrogen	0.83	Freq of Ala-Tyr	0.89	Count of Leucine (L)	0.87
Freq of Gly	0.93	Freq of Leu-Ala	0.86	Freq of Leu	0.78	Freq of carbon	0.90	Freq of Val	0.78	Freq of Lys-Thr	0.88	Count of Tyr	0.83
Freq of Leu-Gly	0.92	Freq of Leu-Leu	0.86	Freq of Ala-Val	0.76	Freq of Thr-Lys	0.89	Freq of Ile	0.74	Freq of Asp-Pro	0.82	Non-reduced Cys Ext coef	0.82
Freq of Leu-Leu	0.92	Freq of Gly	0.86	Freq of Gly	0.76	Freq of Leu-Arg	0.88	Freq of Hydrophilic Res	0.73	Freq of Val-Lys	0.81	Reduced Cys Ext coef	0.82
Freq of Leu-Arg	0.92	Freq of Asn	0.86	Freq of Hydrophobic Residues	0.74	Freq of Leu-Leu	0.88	Freq of Other	0.72	Freq of Thr-Val	0.80	Count of Leu-Phe	0.81
Freq of Ala-Val	0.90	Freq of Pro-Val	0.86	Freq of Gly-Ala	0.74	Freq of Nitrogen	0.88	Freq of Gly	0.67	Freq of Ile-Trp	0.79	Count of Tyr-Lys	0.80
Freq of Hydrophilic Residues	0.89	Freq of Lys-Leu	0.84	Freq of Leu-Leu	0.72	Freq of Val	0.88	Freq of Thr	0.65	Freq of Leu-Leu	0.79	Count of Ile-Leu	0.78
Freq of Val-Lys	0.88	Freq of Ala	0.84	Freq of Ala	0.72	Freq of Thr-His	0.88	Freq of Asp	0.62	Freq of Asn-Gln	0.79	Count of Leu-Tyr	0.77
Freq of Glu-Ala	0.88	Freq of Tryp	0.84	Freq of Leu-Arg	0.71	Freq of Cys	0.88	Freq of His	0.61	Freq of Ser-Cys	0.78	Count of sulfur	0.77
Freq of Thr-Val	0.87	Freq of Tyr	0.84	Freq of Gly-Leu	0.71	Freq of Trp-Pro	0.88	Freq of Phe-Pro	0.61	Freq of Phe-Pro	0.77	Count of Val-Ser	0.72
Freq of Gly-Leu	0.87	Freq of Val-Ser	0.84	Freq of Leu-Gly	0.70	Freq of Asn	0.87	Freq of Val-Ile	0.61	Freq of Gly-Leu	0.77	Count of Ala-Tyr	0.72
Freq of Glu	0.86	Freq of Hydrophobic Residues	0.83	Freq of Val-Lys	0.70	Freq of oxygen	0.87	Freq of Tyr	0.61	Freq of Pro-Arg	0.77	Count of Leu-Leu	0.70
Information gain		Information gain ratio		Rule
Count of hydrogen	1.0	Count of hydrogen	1.0	Freq of hydrophobic residues	1.0
Freq of Leu - Val	0.95	Freq of Glu - Met	0.91	Freq of Ala	1.0
Freq of Thr - Val	0.94	Freq of Gly - Leu	0.91	Freq of hydrogen	o.97
Freq of Val	0.88	Freq of Leu - Leu	0.91	Freq of Gly	0.96
Freq of Leu - Arg	0.87	Freq of Leu	0.91	Freq of Lys	0.96
Freq of Leu	0.86	Freq of Val	0.89	Freq of Asn	0.94
Freq of, Leu - Ala	0.86	Freq of Trp - Pro	0.87	Freq of Val	0.92
Freq of Leu - Leu	0.86	Freq of Ala - Tyr	0.85	Freq of Cys	0.88
Freq of Gly	0.84	Freq of Val - Val	0.80	Freq of Leu	0.87
Freq of Asn	0.84	Freq of Leu - Gly	0.80	Freq of Ser	0.86
Freq of Pro - Val	0.84	Freq of Val - Lys	0.80	Freq of Thr	0.86
Freq of Lys - Leu	0.84			Freq of Leu - Leu	0.85
Freq of Ala	0.84			Freq of hydrophilic residues	0.81
Freq of Trp	0.83
Freq of Tyr	0.81
Freq of Val - Ser	0.81
Freq of hydrophobic residues	0.78

The figures are the value of each features importance assigned by algorithm.

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